Bioengineered Three-Dimensional Physiological Model of Colonic Longitudinal Smooth Muscle In Vitro
نویسندگان
چکیده
منابع مشابه
Bioengineered three-dimensional physiological model of colonic longitudinal smooth muscle in vitro.
BACKGROUND The objective of this study was to develop a physiological model of longitudinal smooth muscle tissue from isolated longitudinal smooth muscle cells arranged in the longitudinal axis. METHODS Longitudinal smooth muscle cells from rabbit sigmoid colon were isolated and expanded in culture. Cells were seeded at high densities onto laminin-coated Sylgard surfaces with defined wavy mic...
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Tissue engineered heart muscle may be able to provide a treatment modality for early stage congestive heart failure. In this study, we describe a new method to engineer functional 3-dimensional heart muscle utilizing a biodegradable fibrin gel. Primary cardiac myocytes were isolated from hearts of 2- to 3-day-old rats and processed in one of the two ways. For the first method (layering approach...
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In this research we evaluated the calcium channel antagonist activity of various diester analohues of nifedipine on rat ileal smooth muscle.in these analogues,the orthophenyl group at position 4 was replaced by 1 methyl 2-meythylsulfonyl or methylthio 5-imidazolyl.wistar rats(180-250g) were killed by a blow to the head.the intestine was removed above the ileucecal junction and longitudinal smoo...
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ژورنال
عنوان ژورنال: Tissue Engineering Part C: Methods
سال: 2010
ISSN: 1937-3384,1937-3392
DOI: 10.1089/ten.tec.2009.0394